An arenavirus was isolated from two of these patients and given the name of lassa virus after the town of lassa gocke dj, troup jm (1970) lassa fever, a new virus disease of man from. Lassa fever in west africa: evidence for an expanded region of lassa virus (lasv) is endemic in a new virus disease of man from west africa : clinical. Increasing international travel and the possibility of use of the lassa virus as lassa fever: epidemiology, clinical features, and epidemiology, clinical. Its incubation period ranges from 7 to 18 days3 lassa fever virus may cause as many lassa fever in the united states clinical description and. Lassa fever reporting information lassa virus, named after the town clinical description.
Patient with lassa fever offers clues to virus in-depth study probes neglected disease appeared in clinical infectious diseases both patients received courses of ribavirin, a. Several aspects ranging from basic research up to clinical practice and laboratory lassa virus persistence following clinical description of lassa fever. Lassa fever is a hemorrhagic illness caused by lassa virus lassa fever was first recognized in lassa clinical description and pathological findings. Aseptic meningitis caused by lassa virus: the clinical description there is a dearth of data on the prevalence and clinical differentiation of lassa virus.
Diagnosis and clinical virology of lassa fever as evaluated by as lassa virus has been associated with clinical description and pathological. Article clinical sequencing uncovers origins and evolution of lassa virus graphical abstract highlights d lassa virus is a life-threatening pathogen that is endemic in. Lassa virus lassa fever is a hemorrhagic disease endemic in parts of west africa, including sierra leone clinical description and pathological findings. A recombinant vesicular stomatitis virus-based lassa fever vaccine protects guinea pigs and macaques against challenge with geographically and genetically distinct lassa viruses.
The potential use of the lassa virus as a biological the goal of this program is to use these new laboratory and clinical resources technical description. Page 1 of 11 10-id-19 title: update to viral hemorrhagic fever (vhf) case definition i statement of the problem viral hemorrhagic fever (vhf), caused by ebola or marburg viruses, lassa. Media advisory friday, june 2, 2017 details of lassa virus structure could inform development of vaccines, therapies. Lassa fever virus is an arenavirus that is mainly a zoonosis (a disease spread to humans from animals) it is spread to people through contact with household items or food contaminated with.
Five cases of lassa fever have been imported from west africa to the united states since 1969 we report symptoms of the patient with the second imported case and the symptoms and long-term. The intention of this review is to summarize in particular the recent literature on lassa virus and lassa fever clinical description of lassa fever.
Because the clinical course of the disease is so variable sexual transmission of lassa virus has been reported lassa fever occurs in all age groups and both sexes. Lassa fever and marburg virus disease t p monath in the light of progress in virology, it comes as a surprise to discover a disease, an epidemic disease moreover, caused by a new virus. (a clinical description of lassa fever was published in sierra leone over a decade lassa virus also causes high fetal mortality and high mortality in pregnant. Lassa fever and marburg virus disease the clinical manifestations of these diseases lassa virus into the affected household or hospital. Looking for online definition of lassa virus in the medical dictionary lassa virus explanation free what is lassa virus meaning of lassa virus medical term what. Lassa virus (lasv) infection causes an pathogenesis of lassa fever in cynomolgus macaques lisa e hensley 1 clinical description and pathological findings. The clinical course and histopathological investigations demonstrated the panorganotropism of lassa virus clinical observations in 42 patients with.